In the past, clinical data showed that some complementary and alternative medicine cam. Cancer adjunct and adjuvant therapies, improving the quality of life. Scutellaria barbata herb uses, benefits, cures, side effects. Don references edit prodromus florae nepalensis, sive enumeratio vegetabilium, quae in itinere per nepaliam proprie dictam et. List of various diseases cured by scutellaria barbata. The modulating effects of preparations of baikal skullcap scutellaria baicalensis on erythron reactions under conditions of neurotic exposures. It should not be confused with scutellaria baicalensis.
Don extract sbe has been shown to have inhibitory effects on numerous human cancers, including hepatoma, lung cancer, colon cancer, skin cancer 1114. The record derives from wcsp data supplied on 20120323 which reports it as an accepted name record 188943 with original publication details. But living in belgium, its hard to find fresh plant material of scutellaria. Lian and has been used as an antiinflammatory and antitumor agent 6, 7. Scutellaria barbata is a common herb in traditional chinese medicine tcm most often used to treat cancer. Chemical composition and antimicrobial activity of the essential oil. Scutellaria baicalensis is an herb used in traditional chinese medicine to treat a variety of conditions including epilepsy, hepatitis, infections, and cancer. Scutellaria barbata barbed skullcap pfaf plant database.
Scutellaria baicalensis, known as chinese skullcap or baikal skullcap, is native to the mountains of eastern asia. Scutellaria barbata has diuretic, antiinflammatory, detoxicant and antitumor properties. Scutellaria barbata has long been used in traditional chinese medicine to treat several illnesses including some cancers. Scutellaria baicalensis is one of approximately 350 scutellaria species.
Scutellaria barbata is a perennial herb prevalent in korea and southern china. Don lamiaceae with potential antineoplastic activity. Names of scutellaria barbata in various languages of the world are also given. It is not a very showy plant and i find it quite interesting that youve managed to keep it in the officeno doubt the plant exerts its influence. Scutellaria barbata has a long history of medical use in traditional chinese medicine for removing heat and toxic material, promoting blood circulation and removing blood stasis, and inducing diuresis to reduce edema. Effects of scutellaria barbata polysaccharide on the. Inhibitory effect of polysaccharides from scutellaria barbata. Scutellaria baicalensis memorial sloan kettering cancer center. Recent pharmacology investigations have provided evidence for its anti cancer, bacteriostasis, anti virus, anti inflammation. Both the root and the aboveground part of scutellaria barbata have been used to make herbal medicines. The lightly toothed leaves are somewhat lanceshaped or triangular and up to about 3 centimeters long.
Evidencebased anticancer materia medica william chi. Scutellaria lateriflora, known commonly as blue skullcap, mad dog skullcap, and sideflowering skullcap, is a hardy perennial herb of the mint family, lamiaceae, native to north america. Scutellaria barbata scutellaria barbata is a species of flowering plant in the mint family, lamiaceae. This approach to cancer care has occurred not because it will prevent. What are the benefits of scutellaria baicalensis scutellaria baicalensis, also known as chinese skullcap, is a perennial flowering plant highly prized for its reputed medicinal properties. In spite of many reports about the cytotoxic and antitumor effects of some species of this genus, anticancer researches on one of the iranian species s. It has also been shown to be safe in a clinical trial of women with advanced breast cancer, and to inhibit cell proliferation.
This study aims to investigate the antitumor effect of the herbpair in bladder cancer cells. Don sb, which is derived from the dried whole plant of labiatae, is a wellknown antiinflammatory and anticancer herb. It was reported that flavonoids and scutebarbatines are the main components of sb 8 10. Effects of scutellaria barbata on cisplatin induced. An extract of this plant, bzl101, has been shown to have anticancer properties in a variety of human cancers. Browse pictures and read growth cultivation information about scutellaria species, barbed skullcap, skullcap scutellaria barbata supplied by member gardeners in. However, the nephrotoxicity which is the sideeffect of cisplatin limits the use of it.
Uvvis analysis of aunps synthesized by scutellaria barbata showed the presence. Scutellaria barbata has been considered to have a good anti tumor activity, often in combination with other traditional chinese medicines in the treatment of primary liver cancer and other gastrointestinal tumors, lung cancer, and cervical cancer and other gynecological cancers, with a better effect perez et al. The lowgrowing plant bears flowers that vary from blue to purple. Scutellaria barbata is an herb that grows in korea and southern china. Gong yanlong1, dong wantao2, song min1 1 clinical college of gansu university of chinese medicine, lanzhou 730000, china. Scutellaria is a genus of flowering plants in the mint family, lamiaceae. The cytotoxic properties of total methanol extract of s. Effective mechanism of bushen jianpi decoction in the treatment of liver based on network pharmacology.
An evidencebased perspective of scutellaria barbata. Effective ingredients, potential targets and mechanism in. It is used along with other herbs in traditional chinese medicine. The anticancer effects and mechanisms of scutellaria. Study reveals how chinese skullcap makes anticancer. Baikal skullcap scutellaria baicalensis plant profiler. Anticancer activity and mechanism of scutellaria barbata extract on human lung cancer cell line a549 article in life sciences 7518. Mineralized auag nanoshells for photothermal antitumor therapy. Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments side effects. Scutellaria barbata memorial sloan kettering cancer center.
Long a mainstay of traditional chinese medicine, skullcap. Activecomponent and integrative mechanism of scutellaria barbata in treatment of cancer based on network pharmacology method. Aug 15, 2010 we have established that bzl101, an aqueous extract from the scutellaria barbata plant, is an effective anticancer agent capable of inducing cell cycle arrest and increasing cell death of hormone sensitive and insensitive, early and late stage, breast and prostate cancer cell lines. The scutellaria species lamiaceae is used as a source of flavonoids to treat a variety of diseases in traditional medicine. It is a perennial herb generally reaching up to 35 centimeters tall, sometimes taller.
Don sb, an antiinflammatory and an antitumor chinese herb, including. May 30, 2011 last month i found out about the phase2 trial of bezielle101, a product based on the scutellaria barbata plant, mainly found in china and for ages used in tcm traditional chinese medicine. Mineralized auag nanoshells for photothermal anti tumor therapy. Stems erect, 123555 cm tall, glabrous or sparsely appressed pubescent upward. Scutellaria species, barbed skullcap, skullcap scutellaria. In vitro studies have demonstrated the anti mutagenesis chemopreventive effect of skullcap via modulating the metabolism of mutagenic compounds such as aflatoxin b 1 and benzoapyrene to reduce their dna binding efficiency. Chemical composition and antimicrobial activity of the essential oil of scutellaria barbata. Jul 09, 2004 a spokeswoman for cancer research uk said. Anticancer activity and mechanism of scutellaria barbata extract on. It has an upright habit, growing 60 to 80 centimeters in maximum height. Ban zhi lian tincture, ban zhi lian, skullcap scutellaria.
However, the anticancer effect of sb and the underlying mechanism require further investigation, particularly its role against metastasis. The anticancer effects and mechanisms of scutellaria barbata d. The species is hermaphrodite has both male and female organs. Scutellaria barbata name synonyms scutellaria adenophylla miq. Medicinal seeds, barbat skullcap, scutellaria barbata, organic seeds, gmo free, heirloom, 100 sees per pack name. May 21, 2015 defects in apoptosis are common phenomena in many types of cancer and are also a critical step in tumorigenesis.
How scutellaria barbata is effective for various diseases is listed in repertory format. The root has been used in traditional chinese medicine to treat cancer of the liver, lung and rectum, and other medical problems. Don may be used as a therapeutic treatment for patients w methods of detecting and treatment of cancers using scutellaria barbata extract bionovo, inc. Definition of herba scutellaria barbata nci drug dictionary. It has been traditionally used in folk medicine as anti inflammatory and anti tumor agents 11, 12. It is in flower from may to july, and the seeds ripen from june to august. Don is an accepted name this name is the accepted name of a species in the genus scutellaria family lamiaceae.
It often is used in combination with other botanicals such as pcspes and shosaikoto. Scutellaria baicalensis root is widely used in china as an adjuvant to chemotherapy for lung cancer. Hedyotis diffusa combined with scutellaria barbata are the. Ban zhi lian has diuretic, antiinflammatory, detoxicant and antitumor properties. Hedyotis diffusa plus scutellaria barbata and scutellaria barbata plus sanzhongkuijiantang were the most common combinations of two hfs used for breast cancer treatment table 4 with a prevalence support factor of 10. Scutellaria barbata known and validated by science for cells protection, immune enhancement and antimutagenic activity. In this study, we evaluated the inhibition of scutellaria barbata d. Skullcap, official scutellaria lateriflora potted plant. Scutellaria barbata, the barbed skullcap, is a species of flowering plant in the mint family, lamiaceae. Apr 11, 2016 a new study, published in the journal science advances, has revealed how the popular chinese herbal remedy huangqin scutellaria baicalensis also known as the chinese skullcap produces. Scutellaria baicalensis memorial sloan kettering cancer. Scutellaria barbata ban zhi lian 30g, was the principle herb, and has a. Don extracts on ovarian cancer and its phytochemicals characterisation article in journal of ethnopharmacology 206.
Current therapeutic role and medicinal potential of. It has also been shown to be safe in a clinical trial of women with advanced breast cancer, and to inhibit cell proliferation and induce ca. The generic name is derived from the latin scutella, meaning a small dish, tray or platter, or little dish, referring to the shape of the calyx. Chinese skullcap is one of the 50 fundamental herbs of traditional chinese medicine. The antimicrobial activity of the oil was evaluated against 17.
Browse pictures and read growth cultivation information about scutellaria species, barbed skullcap, skullcap scutellaria barbata supplied by member gardeners in the plantfiles database at dave. The essential oil of scutellaria barbata was obtained by. Barbated skullcup herb extractmediated biosynthesis of gold. Targeting the apoptotic pathway has been considered an intriguing strategy for cancer therapy. Hedyotis diffusa plus scutellaria barbata induce bladder cancer. Anticancer activity and mechanism of scutellaria barbata. Antitumor effects of traditional chinese medicine targeting. As youve discovered, skullcap scutellaria lateriflora is a shade lover and is cyclic in its growth patterns. Cisplatin is known as one of the most active cytotoxic anti cancer drug. From scutellaria barbata to bzl101 in cancer patients. Scutellaria baicalensis has been shown to have potent anti cancer eff ects for many diff erent types of cancers including colon cancer 19, lung cancer 20, 21, breast cancer 22, 23, leukemias, liver cancer 24, brain cancers 25, stomach cancer 26, and squamous cell carcinomas of the head and neck 27. It is used along with other herbs in traditional chinese medicine to treat bacterial infections, hepatitis, and tumors, and is also used as a diuretic. The results show that hedyotis diffusa plus scutellaria barbata. C524947000 scutellaria barbata extract searchable synonyms, formulas, resource links, and other chemical information.
Don, a perennial herb belonging to the family lamiaceae, is widely distributed throughout china and korea. Bzl101, a phytochemical extract from the scutellaria barbata. Don extracts on ovarian cancer and its phytochemicals characterisation article in journal of ethnopharmacology 206 may 2017 with 50 reads. Analyzing cytotoxic and apoptogenic properties of scutellaria. Buy ban zhi lian tincture, ban zhi lian, skullcap scutellaria barbata herb liquid extract, herbal supplement 2x4 oz on free shipping on qualified orders. Uses, benefits, cures, side effects, nutrients in scutellaria barbata.
Research article open access scutellaria barbata d. So, this finding is very interesting and the active ingredients of the plant should definitely be investigated further. The aim of this study was to examine the anticancer effects and precise regulatory mechanisms of sb in cl15 lung cancer cells. Scutellaria barbata herb advanced breast cancer inspire. Inhibition of tumor growth and immunomodulatory effects of.
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